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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST4
All Species:
15.15
Human Site:
S504
Identified Species:
37.04
UniProt:
Q8WYB5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYB5
NP_036462.2
2073
231378
S504
P
T
P
I
S
G
Q
S
P
S
S
Q
K
S
S
Chimpanzee
Pan troglodytes
XP_519734
1952
219524
E479
G
S
Q
E
I
M
T
E
K
D
M
E
L
F
R
Rhesus Macaque
Macaca mulatta
XP_001094798
1531
171769
D83
V
G
V
T
G
P
P
D
P
Q
V
R
C
P
S
Dog
Lupus familis
XP_536397
2090
233726
S504
P
T
P
I
S
G
Q
S
P
S
S
Q
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRB7
1872
208521
S424
S
S
T
Y
I
S
A
S
T
L
K
V
N
K
K
Rat
Rattus norvegicus
Q5TKR9
1998
223312
R478
S
Q
E
I
M
T
E
R
D
M
E
L
F
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506182
2088
231546
S504
P
T
P
I
S
G
P
S
P
S
S
Q
K
S
S
Chicken
Gallus gallus
XP_421609
2013
224707
S492
P
T
P
I
S
D
Q
S
P
T
S
Q
K
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697383
2011
222731
Q494
P
I
S
L
N
P
T
Q
S
S
S
P
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786050
3082
341137
S615
A
E
E
S
P
A
L
S
K
A
S
E
S
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.2
33.1
94.2
N.A.
82.6
43.8
N.A.
83.6
81.4
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
27.3
Protein Similarity:
100
59.1
46.7
96.1
N.A.
86
58.3
N.A.
89.5
87.9
N.A.
70
N.A.
N.A.
N.A.
N.A.
40.6
P-Site Identity:
100
0
13.3
100
N.A.
6.6
6.6
N.A.
93.3
86.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
13.3
20
100
N.A.
13.3
13.3
N.A.
93.3
93.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
10
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
10
10
0
0
0
0
10
% D
% Glu:
0
10
20
10
0
0
10
10
0
0
10
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% F
% Gly:
10
10
0
0
10
30
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
50
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
10
0
40
10
10
% K
% Leu:
0
0
0
10
0
0
10
0
0
10
0
10
10
0
0
% L
% Met:
0
0
0
0
10
10
0
0
0
10
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
50
0
40
0
10
20
20
0
50
0
0
10
0
20
0
% P
% Gln:
0
10
10
0
0
0
30
10
0
10
0
40
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
10
0
10
10
% R
% Ser:
20
20
10
10
40
10
0
60
10
40
60
0
20
50
60
% S
% Thr:
0
40
10
10
0
10
20
0
10
10
0
0
0
0
0
% T
% Val:
10
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _